The use of calvarial bone graft is a recent advance in craniofacial surgery. Calvarium has multiple potential advantages as a donor source due to least degree of disability and morbidity including pain. In addition, calvarium is a membranous bone which undergoes less resorption and maintains its volume to a significantly greater amount than endochondral bone whet. autografted in the craniofacial region. However, the knowledge of bone graft healing has been well understood and investigated, but donor site healing with the effect of various hemostatics and alloplastic material coralline hydroxyapatite on the subsequent osteoneogenesis have not been reported.
The present study was designed to investigate the effect of gelfoam, bone wax and hydroxyapatite on the early stage of osteoneogenesis at the calvarial bone graft donor site and to compare with the normal progression of bone healing in control group.
In 35 rabbits, four split thickness bony defects were created on the outer table of parietal bone, which were measured 5 x 5 x 2 mm and treated in the following four different manners. 1) control 2) gelfoam 3) bone wax 4) hydrcxyapatite. Each 7 rabbits were sacrificed at 1, 2, 4, 6, 8 weeks after taking a plain skull x-ray film. Both macroscopic and microscopic examinations were done.
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